HIF2A gain-of-function mutations detected in duodenal gangliocytic paraganglioma
نویسندگان
چکیده
منابع مشابه
Duodenal gangliocytic paraganglioma.
We present a case of a 42-year-old man with abdominal pain, obstructive jaundice and a mass in the second portion of the duodenum, near the papillary region. The patient was operated and the histological study of the specimen returned duodenal gangliocytic paraganglioma (a rare submucosal benign tumor of the duodenum). We also describe, after revision of the literature, the pathology, the diagn...
متن کاملGangliocytic paraganglioma of the duodenal papilla associated with esophagogastric adenocarcinoma.
A 3-cm painless epigastric mass was found on examination in 53-year-old man with abdominal pain and vomiting for the past 6 months. An abdominal computed tomography (CT) scan showed asymmetric thickening of the distal esophagus, and upper endoscopy showed a neoplastic lesion in the distal esophagus (histological examination of the biopsy revealed adenocarcinoma). In the duodenum, we found a sub...
متن کاملSCIENTIFIC LETTER Duodenal gangliocytic paraganglioma: Treatment through endoscopic resection
Gangliocytic paraganglioma (GP) is a rare gastrointestinal tumor and 90% of the cases are found in the duodenum, with a predilection for the region of the ampulla of Vater.1--3 The most common clinical presentation includes melena and abdominal pain and it typically follows a benign course.1--3 Surgical resection is the most common treatment and only around 20 cases managed with endoscopic rese...
متن کاملGangliocytic paraganglioma of duodenum
Received 10 October 2012 Accepted 07 February 2013 Early online 25 February 2013 Print 28 February 2013 An elderly person, aged 60 years, presented with pain abdomen localized to the epigastric region, of one year duration. There was a past history of a single episode of passing black-colored tarry stools and hematemesis. Ultrasonography (USG) of abdomen reported a suspected duodenal / periampu...
متن کاملGangliocytic Paraganglioma of Duodenum
Gangliocytic paragangliomas are rare benign tumors which are usually encountered in the second portion of the duodenum. Histogenesis of these tumors is incompletely understood. Patients usually present with upper gastrointestinal bleeding. The endoscopic features of gangliocytic paraganglioma do not differ from those of other submucosal tumors. Therefore, they can be diagnosed histologically by...
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ژورنال
عنوان ژورنال: Endocrine-Related Cancer
سال: 2016
ISSN: 1351-0088,1479-6821
DOI: 10.1530/erc-16-0148